Cloned (Comment) | Organism |
---|---|
expression of TPI in Spodoptera frugiperda Sf21 cells using the baculovirus transfection system | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | TPI phosphorylation by cyclin A/Cdk2 kinase leads to reduced TPI activity, prevented by treatment with olomoucine, a specific inhibitor of Cdk2 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Glyceraldehyde 3-phosphate | Homo sapiens | - |
Glycerone phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | TPI is a direct substrate of cyclin-dependent protein kinase 2, Cdk2, during etoposide-induced apoptosis, analysis by MALDI-TOF peptide finger printing. Phosphorylation of the recombinant TPI by recombinant cyclin A/Cdk2 kinase leading to reduced TPI activity, protection by olomoucine, a specific inhibitor of Cdk2 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Glyceraldehyde 3-phosphate | - |
Homo sapiens | Glycerone phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TpI | - |
Homo sapiens |
Triosephosphate isomerase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in glycolysis | Homo sapiens |