Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1,2,3-propanetriol | isoform AC6 shows about 10% stimulation of activity with 100 mM 1,2,3-propanetriol, isoform AC7 shows about 18% stimulation of activity with 100 mM 1,2,3-propanetriol, isoform AC9 shows about 15% stimulation of activity with 100 mM 1,2,3-propanetriol | Homo sapiens | |
1,2-Butanediol | isoform AC6 shows about 37% stimulation of activity with 100 mM 1,2-butanediol, isoform AC7 shows about 38% stimulation of activity with 100 mM 1,2-butanediol, isoform AC9 shows about 32% stimulation of activity with 100 mM 1,2-butanediol | Homo sapiens | |
1,3-butanediol | isoforms AC6 and AC7 show about 22% stimulation of activity with 100 mM 1,3-butanediol, isoform AC9 shows about 17% stimulation of activity with 100 mM 1,3-butanediol | Homo sapiens | |
1,3-Propanediol | isoform AC6 shows about 17% stimulation of activity with 100 mM 1,3-propanediol, isoform AC7 shows about 20% stimulation of activity with 100 mM 1,3-propanediol, isoform AC9 shows about 17% stimulation of activity with 100 mM 1,3-propanediol | Homo sapiens | |
1,4-Butanediol | isoform AC6 shows about 30% stimulation of activity with 100 mM 1,4-butanediol, isoform AC7 shows about 25% stimulation of activity with 100 mM 1,4-butanediol, isoform AC9 shows about 40% stimulation of activity with 100 mM 1,4-butanediol | Homo sapiens | |
1-butanol | isoform AC6 shows about 85% stimulation of activity with 100 mM 1-butanol, isoform AC7 shows about 110% stimulation of activity with 100 mM 1-butanol, isoform AC9 shows about 105% stimulation of activity with 100 mM 1-butanol | Homo sapiens | |
1-propanol | isoform AC6 shows about 31% stimulation of activity with 100 mM 1-propanol, isoform AC7 shows about 50% stimulation of activity with 100 mM 1-propanol, isoform AC9 shows about 44% stimulation of activity with 100 mM 1-propanol | Homo sapiens | |
2,3-Butanediol | isoform AC6 shows about 30% stimulation of activity with 100 mM 2,3-butanediol, isoform AC7 shows about 35% stimulation of activity with 100 mM 2,3-butanediol, isoform AC9 shows about 41% stimulation of activity with 100 mM 2,3-butanediol | Homo sapiens | |
2-butanol | isoform AC6 shows about 60% stimulation of activity with 100 mM 2-butanol, isoform AC7 shows about 70% stimulation of activity with 100 mM 2-butanol, isoform AC9 shows about 60% stimulation of activity with 100 mM 2-butanol | Homo sapiens | |
2-propanol | isoform AC6 shows about 20% stimulation of activity with 100 mM 2-propanol, isoform AC7 shows about 35% stimulation of activity with 100 mM 2-propanol, isoform AC9 shows about 40% stimulation of activity with 100 mM 2-propanol | Homo sapiens | |
D-(-)-2,3-butanediol | isoforms AC6 and AC7show about 30% stimulation of activity with 100 mM D-(-)-2,3-butanediol, isoform AC9 shows about 10% stimulation of activity with 100 mM D-(-)-2,3-butanediol | Homo sapiens | |
D1A dopamine receptor | - |
Homo sapiens | |
ethanol | stimulates isoform AC6, AC7 and AC9 activity | Homo sapiens | |
L-(+)-2,3-butanediol | isoform AC6 shows about 55% stimulation of activity with 100 mM L-(+)-2,3-butanediol, isoform AC9 shows about 45% stimulation of activity with 100 mM L-(+)-2,3-butanediol | Homo sapiens | |
meso-2,3-butanediol | isoform AC6 shows about 15% stimulation of activity with 100 mM meso-2,3-butanediol, isoform AC7 shows about 28% stimulation of activity with 100 mM meso-2,3-butanediol, isoform AC9 shows about 10% stimulation of activity with 100 mM meso-2,3-butanediol | Homo sapiens | |
additional information | isoforms AC6, AC7 and AC9 are not significantly stimulated by 1,2,4-butanetriol and 1,2,3,4-butanetetraol | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-(+)-2,3-butanediol | isoform AC7 activity is inhibited to about 50% with 100 mM L-(+)-2,3-butanediol | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Homo sapiens | 3',5'-cyclic-AMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AC6 | isoform | Homo sapiens |
AC7 | isoform | Homo sapiens |
AC9 | isoform | Homo sapiens |
adenylyl cyclase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | - |
Homo sapiens |