Protein Variants | Comment | Organism |
---|---|---|
E187Q | K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate | Oryctolagus cuniculus |
K107M | K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate | Oryctolagus cuniculus |
K146M | K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate | Oryctolagus cuniculus |
K229A | K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate | Oryctolagus cuniculus |
K229M | K107M, K146M, K229M, K229A and E187Q, have decreased cleavage activity towards D-fructose 1,6-bisphosphate | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,4-Dihydroxybenzaldehyde 4-phosphate | - |
Oryctolagus cuniculus | |
4-Hydroxybenzaldehyde phosphate | competitive | Oryctolagus cuniculus | |
Hydroquinone diphosphate | competitive | Oryctolagus cuniculus | |
Resorcinol diphosphate | competitive | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate | proton-transfer mechanism involving Lys-229, Glu-187 and Lys-146 | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate | - |
Oryctolagus cuniculus | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | turnover-numbers of wild-type and mutant enzymes | Oryctolagus cuniculus |