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Literature summary for 4.1.2.13 extracted from

  • Lebherz, H.G.; Rutter, W.J.
    The class I (Schiff base) fructose-diphosphate aldolase of Peptococcus aerogenes (1975), Methods Enzymol., 42C, 249-258.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
NaBH4 inactivation Peptoniphilus asaccharolyticus

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metal requirement Peptoniphilus asaccharolyticus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
-
Peptoniphilus asaccharolyticus

Organism

Organism UniProt Comment Textmining
Peptoniphilus asaccharolyticus
-
-
-
Peptoniphilus asaccharolyticus 228
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Peptoniphilus asaccharolyticus

Reaction

Reaction Comment Organism Reaction ID
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate in class I fructose diphosphate aldolases a Schiff base intermediate is formed between glycerone phosphate or fructose 1,6-diphosphate and an epsilon-amino group of a Lys residue at the active site of the enzyme Peptoniphilus asaccharolyticus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
14.8
-
-
Peptoniphilus asaccharolyticus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-bisphosphate
-
Peptoniphilus asaccharolyticus glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?
D-fructose 1,6-bisphosphate
-
Peptoniphilus asaccharolyticus 228 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
?
D-Fructose 1-phosphate
-
Peptoniphilus asaccharolyticus Glycerone phosphate + D-glyceraldehyde
-
?
D-Fructose 1-phosphate
-
Peptoniphilus asaccharolyticus 228 Glycerone phosphate + D-glyceraldehyde
-
?

Subunits

Subunits Comment Organism
monomer 1 * 33000 Peptoniphilus asaccharolyticus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5 8.5 with D-fructose 1,6-bisphosphate as substrate Peptoniphilus asaccharolyticus
7.5
-
with fructose 1-phosphate as substrate Peptoniphilus asaccharolyticus