Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate + CO2 | Mus musculus | - |
ATP + oxaloacetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Leydig cell | - |
Mus musculus | - |
testis | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate + CO2 | - |
Mus musculus | ATP + oxaloacetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADP-linked PEP carboxykinase | - |
Mus musculus |
PEPCK | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | pubertal mouse (8-week-old) testes and human chorionic gonadotropin-induced prepubertal mouse testes show increased enzyme expression | up |
General Information | Comment | Organism |
---|---|---|
malfunction | lack of phosphoenolpyruvate carboxykinase leads to activation of AMP-activated protein kinase, which inhibits cAMP-induced steroidogenic gene promoter activity and gene expression | Mus musculus |
physiological function | the enzyme is required for steroidogenesis in testicular Leydig cells | Mus musculus |