Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
perinuclear space | localizes in eukaryotic cells to the perinuclear region | Pseudomonas aeruginosa | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | the full-length form is processed to a soluble fragment, which possesses both the GAP and ADP-ribosyltransferase activities | Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + (ADP-D-ribosyl)n-acceptor | ExoS is a type III cytotoxin which modulates two eukaryotic signalling pathways. The N-terminus (residues 1-234) is a GTPase activating protein for RhoGTPases, while the C-terminus (residues 232-453) encodes an ADP-ribosyltransferase | Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ExoS | - |
Pseudomonas aeruginosa |