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Literature summary for 2.4.1.21 extracted from

  • Zhou, H.; Wang, L.; Liu, G.; Meng, X.; Jing, Y.; Shu, X.; Kong, X.; Sun, J.; Yu, H.; Smith, S.M.; Wu, D.; Li, J.
    Critical roles of soluble starch synthase SSIIIa and granule-bound starch synthase Waxy in synthesizing resistant starch in rice (2016), Proc. Natl. Acad. Sci. USA, 113, 12844-12849 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
food industry resistant starch (RS) has the potential to protect against diabetes and reduce the incidence of diarrhea, inflammatory bowel disease, colon cancer, and chronic renal and hepatic diseases. Soluble starch synthase SSIIIa has a critical role in synthesizing resistant starch in rice Oryza sativa

Localization

Localization Comment Organism GeneOntology No. Textmining
plastid
-
Oryza sativa 9536
-
soluble
-
Oryza sativa
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP-alpha-D-glucose + [(1->4)-alpha-D-glucosyl]n Oryza sativa
-
ADP + [(1->4)-alpha-D-glucosyl]n+1
-
?

Organism

Organism UniProt Comment Textmining
Oryza sativa
-
-
-
Oryza sativa
-
var. indica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP-alpha-D-glucose + amylopectin
-
Oryza sativa ADP + ?
-
?
ADP-alpha-D-glucose + [(1->4)-alpha-D-glucosyl]n
-
Oryza sativa ADP + [(1->4)-alpha-D-glucosyl]n+1
-
?

Subunits

Subunits Comment Organism
? x * 250000, SDS-PAGE Oryza sativa

Synonyms

Synonyms Comment Organism
SSIIIa
-
Oryza sativa
starch synthase IIIa
-
Oryza sativa

General Information

General Information Comment Organism
malfunction mutations in the starch synthase IIIa gene, in combination with a highly expressed Waxy gene, lead to a high level of resistant starch Oryza sativa
physiological function grain qualities and physicochemical properties of starch are determined by SSIIIa. Biosynthesis of resistant starch is regulated by SSIIIa. Mutation of SSIIIa gene results in elevation of resistant starch Oryza sativa