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Literature summary for 2.4.1.17 extracted from
- Characterization of function and genetic feature of UDP-glucuronosyltransferase in avian species (2019), Comp. Biochem. Physiol. C, 217, 5-14 .
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.003188 | - |
1-hydroxypyrene | at pH 7.4 and 38.5°C | Struthio camelus |  |
| 0.004246 | - |
beta-estradiol | at pH 7.4 and 39°C | Spheniscus humboldti | |
| 0.004951 | - |
acetaminophen | at pH 7.4 and 42°C | Gallus gallus | |
| 0.005299 | - |
acetaminophen | at pH 7.4 and 38.5°C | Rattus norvegicus | |
| 0.00787 | - |
beta-estradiol | at pH 7.4 and 42°C | Gallus gallus | |
| 0.01108 | - |
acetaminophen | at pH 7.4 and 39.5°C | Bubo virginianus | |
| 0.01214 | - |
beta-estradiol | at pH 7.4 and 38.5°C | Rattus norvegicus | |
| 0.01251 | - |
beta-estradiol | at pH 7.4 and 40.5°C | Haliaeetus albicilla | |
| 0.01412 | - |
beta-estradiol | at pH 7.4 and 41.5°C | Meleagris gallopavo | |
| 0.01591 | - |
acetaminophen | at pH 7.4 and 38.5°C | Serinus canaria | |
| 0.019 | - |
1-hydroxypyrene | at pH 7.4 and 38.5°C | Serinus canaria | |
| 0.02304 | - |
beta-estradiol | at pH 7.4 and 39.5°C | Bubo virginianus | |
| 0.02364 | - |
acetaminophen | at pH 7.4 and 40.5°C | Haliaeetus albicilla | |
| 0.02548 | - |
1-hydroxypyrene | at pH 7.4 and 40.5°C | Haliaeetus albicilla | |
| 0.02908 | - |
beta-estradiol | at pH 7.4 and 38.5°C | Serinus canaria | |
| 0.03512 | - |
beta-estradiol | at pH 7.4 and 38.5°C | Struthio camelus | |
| 0.03662 | - |
1-hydroxypyrene | at pH 7.4 and 41.5°C | Meleagris gallopavo | |
| 0.04134 | - |
acetaminophen | at pH 7.4 and 41.5°C | Meleagris gallopavo | |
| 0.06745 | - |
1-hydroxypyrene | at pH 7.4 and 38.5°C | Rattus norvegicus | |
| 0.09979 | - |
acetaminophen | at pH 7.4 and 38.5°C | Struthio camelus | |
| 0.1137 | - |
1-hydroxypyrene | at pH 7.4 and 42°C | Gallus gallus | |
| 2.326 | - |
1-hydroxypyrene | at pH 7.4 and 39°C | Spheniscus humboldti | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Gallus gallus | - |
- |
| microsome | - |
Meleagris gallopavo | - |
- |
| microsome | - |
Rattus norvegicus | - |
- |
| microsome | - |
Struthio camelus | - |
- |
| microsome | - |
Serinus canaria | - |
- |
| microsome | - |
Bubo virginianus | - |
- |
| microsome | - |
Haliaeetus albicilla | - |
- |
| microsome | - |
Spheniscus humboldti | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 100 mM used in assay conditions | Gallus gallus | |
| Mg2+ | 100 mM used in assay conditions | Meleagris gallopavo | |
| Mg2+ | 100 mM used in assay conditions | Rattus norvegicus | |
| Mg2+ | 100 mM used in assay conditions | Struthio camelus | |
| Mg2+ | 100 mM used in assay conditions | Serinus canaria | |
| Mg2+ | 100 mM used in assay conditions | Bubo virginianus | |
| Mg2+ | 100 mM used in assay conditions | Haliaeetus albicilla | |
| Mg2+ | 100 mM used in assay conditions | Spheniscus humboldti | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bubo virginianus | - |
great horned owl | - |
| Gallus gallus | - |
- |
- |
| Haliaeetus albicilla | - |
white-tailed eagle | - |
| Meleagris gallopavo | - |
turkey | - |
| Rattus norvegicus | - |
- |
- |
| Serinus canaria | - |
canary | - |
| Spheniscus humboldti | - |
Humboldt penguin | - |
| Struthio camelus | - |
ostrich | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Gallus gallus | - |
| liver | - |
Meleagris gallopavo | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Struthio camelus | - |
| liver | - |
Serinus canaria | - |
| liver | - |
Bubo virginianus | - |
| liver | - |
Haliaeetus albicilla | - |
| liver | - |
Spheniscus humboldti | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-hydroxypyrene + UDP-glucuronate | - |
Gallus gallus | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Meleagris gallopavo | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Rattus norvegicus | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Struthio camelus | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Serinus canaria | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Bubo virginianus | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Haliaeetus albicilla | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| 1-hydroxypyrene + UDP-glucuronate | - |
Spheniscus humboldti | UDP + 1-hydroxypyrene-1-O-glucuronide | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Gallus gallus | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Meleagris gallopavo | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Rattus norvegicus | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Struthio camelus | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Serinus canaria | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Bubo virginianus | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Haliaeetus albicilla | UDP + ? | - |
? | |
| acetaminophen + UDP-glucuronate | - |
Spheniscus humboldti | UDP + ? | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Gallus gallus | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Meleagris gallopavo | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Rattus norvegicus | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Struthio camelus | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Serinus canaria | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Bubo virginianus | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Haliaeetus albicilla | UDP + beta-estradiol-3-glucuronide | - |
? | |
| beta-estradiol + UDP-glucuronate | - |
Spheniscus humboldti | UDP + beta-estradiol-3-glucuronide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UDP-glucuronosyltransferase | - |
Gallus gallus |
| UDP-glucuronosyltransferase | - |
Meleagris gallopavo |
| UDP-glucuronosyltransferase | - |
Rattus norvegicus |
| UDP-glucuronosyltransferase | - |
Struthio camelus |
| UDP-glucuronosyltransferase | - |
Serinus canaria |
| UDP-glucuronosyltransferase | - |
Bubo virginianus |
| UDP-glucuronosyltransferase | - |
Haliaeetus albicilla |
| UDP-glucuronosyltransferase | - |
Spheniscus humboldti |
| UGT1E | isoform | Gallus gallus |
| UGT1E | isoform | Meleagris gallopavo |
| UGT1E | isoform | Rattus norvegicus |
| UGT1E | isoform | Struthio camelus |
| UGT1E | isoform | Serinus canaria |
| UGT1E | isoform | Bubo virginianus |
| UGT1E | isoform | Haliaeetus albicilla |
| UGT1E | isoform | Spheniscus humboldti |
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