Cloned (Comment) | Organism |
---|---|
gene UGT1A1, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A1, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A10, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A10, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A11, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A2, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A3, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A3, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A4, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A4, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A5, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A6, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A6, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A7, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A7, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A8, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A8, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
gene UGT1A9, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of dog and human UGT1As | Homo sapiens |
gene UGT1A9, cloning from genomic DNA and hepatic cDNA, phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Canis lupus familiaris | - |
- |
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
beagle dogs | - |
Canis lupus familiaris | Q95M37 | beagle dogs | - |
Homo sapiens | O60656 | - |
- |
Homo sapiens | P19224 | - |
- |
Homo sapiens | P22309 | - |
- |
Homo sapiens | P22310 | - |
- |
Homo sapiens | P35503 | - |
- |
Homo sapiens | P35504 | - |
- |
Homo sapiens | Q9HAW7 | - |
- |
Homo sapiens | Q9HAW8 | - |
- |
Homo sapiens | Q9HAW9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Canis lupus familiaris | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 UDP-D-glucuronate + 2 dexmedetomidine | low activity | Homo sapiens | 2 UDP + dexmedetomidine N1-beta-D-glucuronoside + dexmedetomidine N3-beta-D-glucuronoside | - |
? | |
2 UDP-D-glucuronate + 2 dexmedetomidine | veryl low activity | Homo sapiens | 2 UDP + dexmedetomidine N1-beta-D-glucuronoside + dexmedetomidine N3-beta-D-glucuronoside | - |
? | |
additional information | no activity with bilirubin, 17-alpha-estradiol, 17-beta-estradiol, dexmedetomidine, entacapone, levomedetomidine, diclofenac, indomethacin, 4-methylumbelliferone, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no activity with bilirubin, 4-methylumbelliferone, (R)-propranolol, (S)-propranolol, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no activity with bilirubin, dexmedetomidine, levomedetomidine, and S-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no activity with bilirubin, ethinylestradiol, 17-beta-estradiol, dexmedetomidine, and levomedetomidine, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no activity with bilirubin, ethinylestradiol, 17beta- and 17alpha-estradiol, diclofenac, entacapone, 4-methylumbelliferone, indomethacin, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no activity with dexmedetomidine, levomedetomidine, 4-methylumbelliferone, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no or poor activity with 4-methylumbelliferone, dexmedetomidine, levomedetomidine, and S-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no or poor activity with bilirubin, 17-alpha-estradiol, 17-beta-estradiol, dexmedetomidine, levomedetomidine, diclofenac, indomethacin, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no or poor activity with bilirubin, dexmedetomidine, diclofenac, levomedetomidine, (R)-propranolol, (S)-propranolol, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no or poor activity with bilirubin, ethinylestradiol, 17-alpha-estradiol, 17-beta-estradiol, levomedetomidine, dexmedetomidine, diclofenac, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no or poor activity with bilirubin, levomedetomidine, and dexmedetomidine, substrate specificities of isozymes, overview | Homo sapiens | ? | - |
? | |
additional information | no or poor activity with bilirubin, levomedetomidine, dexmedetomidine, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no or poor activity with bilirubin, levomedetomidine, dexmedetomidine, and (R)-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no or poor activity with bilirubin, levomedetomidine, dexmedetomidine, indomethacin, and (S)-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no or poor activity with bilirubin,levomedetomidine, dexmedetomidine, diclofenac, 4-methylumbelliferone, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
additional information | no or poor activity with levomedetomidine, 4-methylumbelliferone, dexmedetomidine, (R)-propranolol, and (S)-propranolol, substrate specificities of isozymes, overview | Canis lupus familiaris | ? | - |
? | |
UDP-alpha-D-glucuronate + (R)-propranolol | - |
Canis lupus familiaris | UDP + (R)-propranolol beta-D-glucuronoside | - |
? | |
UDP-alpha-D-glucuronate + (R)-propranolol | - |
Homo sapiens | UDP + (R)-propranolol beta-D-glucuronoside | - |
? | |
UDP-alpha-D-glucuronate + (R)-propranolol | high activity | Homo sapiens | UDP + (R)-propranolol beta-D-glucuronoside | - |
? | |
UDP-alpha-D-glucuronate + (S)-propranolol | - |
Canis lupus familiaris | UDP + (S)-propranolol beta-D-glucuronoside | - |
? | |
UDP-alpha-D-glucuronate + (S)-propranolol | - |
Homo sapiens | UDP + (S)-propranolol beta-D-glucuronoside | - |
? | |
UDP-alpha-D-glucuronate + (S)-propranolol | very low activity | Canis lupus familiaris | UDP + (S)-propranolol beta-D-glucuronoside | - |
? | |
UDP-alpha-D-glucuronate + (S)-propranolol | high activity | Homo sapiens | UDP + (S)-propranolol beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | - |
Canis lupus familiaris | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | very low activity | Homo sapiens | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | low activity | Canis lupus familiaris | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | low activity | Homo sapiens | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | good substrate | Canis lupus familiaris | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | lower activity | Homo sapiens | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | higher activity | Canis lupus familiaris | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-alpha-estradiol | very high activity with UGT1A10 | Homo sapiens | UDP + 17-alpha-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-beta-estradiol | - |
Canis lupus familiaris | UDP + 17-beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-beta-estradiol | low activity | Canis lupus familiaris | UDP + 17-beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-beta-estradiol | low activity | Homo sapiens | UDP + 17-beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-beta-estradiol | lower activity | Homo sapiens | UDP + 17-beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 17-beta-estradiol | very high activity | Homo sapiens | UDP + 17-beta-estradiol 3-O-beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-methylumbelliferone | - |
Canis lupus familiaris | UDP + 4-methylumbelliferyl beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-methylumbelliferone | - |
Homo sapiens | UDP + 4-methylumbelliferyl beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-methylumbelliferone | low activity | Canis lupus familiaris | UDP + 4-methylumbelliferyl beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-methylumbelliferone | high activity | Homo sapiens | UDP + 4-methylumbelliferyl beta-D-glucuronoside | - |
? | |
UDP-glucuronate + 4-methylumbelliferone | high activity | Canis lupus familiaris | UDP + 4-methylumbelliferyl beta-D-glucuronoside | - |
? | |
UDP-glucuronate + bilirubin | - |
Canis lupus familiaris | UDP + bilirubin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + bilirubin | very low activity | Canis lupus familiaris | UDP + bilirubin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + bilirubin | very high activity | Homo sapiens | UDP + bilirubin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + diclofenac | - |
Canis lupus familiaris | UDP + diclofenac beta-D-glucuronoside | - |
? | |
UDP-glucuronate + diclofenac | very low activity | Canis lupus familiaris | UDP + diclofenac beta-D-glucuronoside | - |
? | |
UDP-glucuronate + diclofenac | very low activity | Homo sapiens | UDP + diclofenac beta-D-glucuronoside | - |
? | |
UDP-glucuronate + diclofenac | low activity | Canis lupus familiaris | UDP + diclofenac beta-D-glucuronoside | - |
? | |
UDP-glucuronate + diclofenac | low activity | Homo sapiens | UDP + diclofenac beta-D-glucuronoside | - |
? | |
UDP-glucuronate + diclofenac | high activity | Homo sapiens | UDP + diclofenac beta-D-glucuronoside | - |
? | |
UDP-glucuronate + entacapone | - |
Canis lupus familiaris | UDP + entacapone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + entacapone | very low activity | Homo sapiens | UDP + entacapone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + entacapone | low activity | Homo sapiens | UDP + entacapone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + entacapone | high activity | Canis lupus familiaris | UDP + entacapone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + entacapone | high activity | Homo sapiens | UDP + entacapone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + entacapone | very high activity | Homo sapiens | UDP + entacapone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + epitestosterone | - |
Canis lupus familiaris | UDP + epitestosterone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + epitestosterone | - |
Homo sapiens | UDP + epitestosterone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + ethinylestradiol | - |
Canis lupus familiaris | UDP + ethinylestradiol beta-D-glucuronoside | - |
? | |
UDP-glucuronate + ethinylestradiol | - |
Homo sapiens | UDP + ethinylestradiol beta-D-glucuronoside | - |
? | |
UDP-glucuronate + ethinylestradiol | very low activity | Canis lupus familiaris | UDP + ethinylestradiol beta-D-glucuronoside | - |
? | |
UDP-glucuronate + ethinylestradiol | very low activity | Homo sapiens | UDP + ethinylestradiol beta-D-glucuronoside | - |
? | |
UDP-glucuronate + ethinylestradiol | low activity | Canis lupus familiaris | UDP + ethinylestradiol beta-D-glucuronoside | - |
? | |
UDP-glucuronate + indomethacin | - |
Canis lupus familiaris | UDP + indomethacin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + indomethacin | - |
Homo sapiens | UDP + indomethacin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + indomethacin | very low activity | Homo sapiens | UDP + indomethacin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + indomethacin | low activity | Canis lupus familiaris | UDP + indomethacin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + indomethacin | low activity | Homo sapiens | UDP + indomethacin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + indomethacin | high activity | Homo sapiens | UDP + indomethacin beta-D-glucuronoside | - |
? | |
UDP-glucuronate + levomedetomidine | - |
Homo sapiens | UDP + levomedetomidine beta-D-glucuronoside | - |
? | |
UDP-glucuronate + levomedetomidine | low activity | Homo sapiens | UDP + levomedetomidine beta-D-glucuronoside | - |
? | |
UDP-glucuronate + testosterone | - |
Canis lupus familiaris | UDP + testosterone beta-D-glucuronoside | - |
? | |
UDP-glucuronate + testosterone | - |
Homo sapiens | UDP + testosterone beta-D-glucuronoside | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucuronosyltransferase | - |
Canis lupus familiaris |
UDP-glucuronosyltransferase | - |
Homo sapiens |
UGT1A1 | - |
Canis lupus familiaris |
UGT1A1 | - |
Homo sapiens |
UGT1A10 | - |
Canis lupus familiaris |
UGT1A10 | - |
Homo sapiens |
UGT1A11 | - |
Canis lupus familiaris |
UGT1A2 | - |
Canis lupus familiaris |
UGT1A3 | - |
Canis lupus familiaris |
UGT1A3 | - |
Homo sapiens |
UGT1A4 | - |
Canis lupus familiaris |
UGT1A4 | - |
Homo sapiens |
UGT1A5 | - |
Homo sapiens |
UGT1A6 | - |
Homo sapiens |
UGT1A6 | - |
Canis lupus familiaris |
UGT1A7 | - |
Canis lupus familiaris |
UGT1A7 | - |
Homo sapiens |
UGT1A8 | - |
Canis lupus familiaris |
UGT1A8 | - |
Homo sapiens |
UGT1A9 | - |
Canis lupus familiaris |
UGT1A9 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
evolution | phylogenetic analysis of dog and human UGT1As | Homo sapiens |
evolution | phylogenetic analysis of the dog and human UGT1As | Canis lupus familiaris |