Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NH4Cl | 1.0 M | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.063 | - |
gonadotropin releasing hormone | - |
Bos taurus | |
0.088 | - |
[Gln1,Gly4]-thyrotropin releasing hormone | - |
Bos taurus | |
0.132 | - |
L-Gln-L-Thr-L-Ala | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
secretory granule | - |
Bos taurus | 30141 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutaminyl-peptide | Rattus norvegicus | - |
5-oxoprolyl-peptide + NH3 | - |
? | |
L-glutaminyl-peptide | Bos taurus | the enzyme may participate in the posttranslational processing of hormonal precursors to pyroglutamyl peptides | 5-oxoprolyl-peptide + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
brain | - |
Bos taurus | - |
hypothalamus | - |
Rattus norvegicus | - |
pituitary gland | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
gonadotropin releasing hormone | - |
Bos taurus | ? | - |
? | |
L-Gln-L-Thr-L-Ala | - |
Bos taurus | 5-oxoprolyl-L-Thr-L-Ala + NH3 | - |
? | |
L-glutaminyl-peptide | - |
Rattus norvegicus | 5-oxoprolyl-peptide + NH3 | - |
? | |
L-glutaminyl-peptide | thyrotropin-releasing hormone | Rattus norvegicus | 5-oxoprolyl-peptide + NH3 | - |
? | |
L-glutaminyl-peptide | thyrotropin-releasing hormone | Bos taurus | 5-oxoprolyl-peptide + NH3 | - |
? | |
L-glutaminyl-peptide | Gln-His-Pro-Glythyrotropin-releasing hormone, gonadotropin-releasing hormone and L-Gln-Tyr-Ala | Rattus norvegicus | 5-oxoprolyl-peptide + NH3 | - |
? | |
L-glutaminyl-peptide | Gln-His-Pro-Glythyrotropin-releasing hormone, gonadotropin-releasing hormone and L-Gln-Tyr-Ala | Bos taurus | 5-oxoprolyl-peptide + NH3 | - |
? | |
L-glutaminyl-peptide | the enzyme may participate in the posttranslational processing of hormonal precursors to pyroglutamyl peptides | Bos taurus | 5-oxoprolyl-peptide + NH3 | - |
? | |
additional information | no substrates are D-Gln-Tyr-Ala and Lys-Arg-Gln-His-Pro-Gly-Lys-Arg, i.e. thyrotropin releasing hormone precursor | Rattus norvegicus | ? | - |
? | |
additional information | no substrates are D-Gln-Tyr-Ala and Lys-Arg-Gln-His-Pro-Gly-Lys-Arg, i.e. thyrotropin releasing hormone precursor | Bos taurus | ? | - |
? | |
[Gln1,Gly4]-thyrotropin releasing hormone | - |
Bos taurus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Bos taurus |