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Literature summary for extracted from

  • Piano, V.; Nenci, S.; Magnani, F.; Aliverti, A.; Mattevi, A.
    Recombinant human dihydroxyacetonephosphate acyl-transferase characterization as an integral monotopic membrane protein (2016), Biochem. Biophys. Res. Commun., 481, 51-58 .
    View publication on PubMedView publication on EuropePMC


Cloned (Comment) Organism
expressed in HEK-293E cells and Pichia pastoris KM71H MutS strain Homo sapiens


Protein Variants Comment Organism
DHAPATDELTA135 the mutant enzyme is completely inactive Homo sapiens

General Stability

General Stability Organism
the enzyme activity and stability is dependent on alkyl-dihydroxyacetone phosphate synthase presence Homo sapiens


Localization Comment Organism GeneOntology No. Textmining
peroxisomal membrane inner side of the peroxisomal membrane Homo sapiens 5778

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + glycerone phosphate Homo sapiens
CoA + acylglycerone phosphate


Organism UniProt Comment Textmining
Homo sapiens O15228

Purification (Commentary)

Purification (Comment) Organism
Ni-Sepharose resin column chromatography, His-Trap column chromatography and Superdex S200 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + glycerone phosphate
Homo sapiens CoA + acylglycerone phosphate


Subunits Comment Organism
? x * 70000, recombinant enzyme, SDS-PAGE Homo sapiens
? x * 109000, recombinant enzyme fused to enhanced green fluorescent protein, SDS-PAGE Homo sapiens


Synonyms Comment Organism
Homo sapiens
dihydroxyacetone phosphate acyl-transferase
Homo sapiens