Protein Variants | Comment | Organism |
---|---|---|
additional information | linkage of two subunits into a single polypeptide chain dimer 2XALAS, results in enzyme with about 7fold greater turnover number than wild-type and with greater A410/A330 ratio | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.45 | - |
succinyl-CoA | pH 7.5, 30°C, mutant 2XALAS | Mus musculus | |
0.63 | - |
succinyl-CoA | pH 7.5, 20°C, mutant 2XALAS | Mus musculus | |
2 | 3 | glycine | pH 7.5, 30°C, wild-type | Mus musculus | |
2.3 | - |
succinyl-CoA | pH 7.5, 30°C, wild-type | Mus musculus | |
11 | - |
succinyl-CoA | pH 7.5, 20°C, wild-type | Mus musculus | |
11.7 | - |
glycine | pH 7.5, 20°C, mutant 2XALAS | Mus musculus | |
14 | - |
glycine | pH 7.5, 20°C, wild-type | Mus musculus | |
16.7 | - |
glycine | pH 7.5, 30°C, mutant 2XALAS | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
erythroid specific isoform | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | - |
Mus musculus | 5-aminolevulinate + CoA + CO2 | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.016 | - |
glycine | pH 7.5, 20°C, wild-type | Mus musculus | |
0.11 | - |
glycine | pH 7.5, 20°C, mutant 2XALAS | Mus musculus | |
0.167 | - |
glycine | pH 7.5, 30°C, wild-type | Mus musculus | |
0.92 | - |
glycine | pH 7.5, 30°C, mutant 2XALAS | Mus musculus |