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Literature summary for 2.3.1.159 extracted from

  • Junghanns, K.T.; Kneusel, R.E.; Groger, D.; Matern, U.
    Differential regulation and distribution of acridone synthase in Ruta graveolens (1998), Phytochemistry, 49, 403-411.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information induced activity by addition of crude elicitors from the cell wall of Phytophthora megasperma f. sp. glycinea, syn. Phytophthora sojae Ruta graveolens

Inhibitors

Inhibitors Comment Organism Structure
additional information light irradiation decreases activity Ruta graveolens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malonyl-CoA + N-methylanthraniloyl-CoA Ruta graveolens activity is increased upon treatment with crude elicitors from the cell wall of Phytophthora megasperma f. sp. glycinea, syn. Phytophthora sojae, and decreased upon light irradiation CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
?
malonyl-CoA + N-methylanthraniloyl-CoA Ruta graveolens involved in the biosynthesis of all acridone alkaloids CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
?

Organism

Organism UniProt Comment Textmining
Ruta graveolens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture strain R-20 Ruta graveolens
-
hypocotyl endodermis and vascular tissue, mRNA and protein Ruta graveolens
-
root adjacent to the rhizodermis, mRNA and protein Ruta graveolens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
malonyl-CoA + N-methylanthraniloyl-CoA
-
Ruta graveolens CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
?
malonyl-CoA + N-methylanthraniloyl-CoA activity is increased upon treatment with crude elicitors from the cell wall of Phytophthora megasperma f. sp. glycinea, syn. Phytophthora sojae, and decreased upon light irradiation Ruta graveolens CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
?
malonyl-CoA + N-methylanthraniloyl-CoA involved in the biosynthesis of all acridone alkaloids Ruta graveolens CoA + 1,3-dihydroxy-N-methylacridone + CO2
-
?

Synonyms

Synonyms Comment Organism
ACS
-
Ruta graveolens