Literature summary for 2.1.1.382 extracted from

Kaufmann, F.; Wohlfarth, G.; Diekert, G.
O-Demethylase from Acetobacterium dehalogenans Substrate specificity and function of the participating proteins (1998), Eur. J. Biochem., 253, 706-711 .

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Organism

Organism	UniProt	Comment	Textmining
Acetobacterium dehalogenans	O87604	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-hydroxyanisole + [Co(I) methoxylated corrinoid protein OdmA]	67% of the activity with vanillate, O-demethylase complex	Acetobacterium dehalogenans	[methyl-Co(III) methoxylated corrinoid protein OdmA] + 1,2-dihydroxybenzol	-	?
isovanillate + [Co(I) methoxylated corrinoid protein OdmA]	26% of the activity with vanillate, O-demethylase complex	Acetobacterium dehalogenans	[methyl-Co(III) methoxylated corrinoid protein OdmA] + 3,4-dihydroxybenzoate	-	?
syringate + [Co(I) methoxylated corrinoid protein OdmA]	54% of the activity with vanillate, O-demethylase complex	Acetobacterium dehalogenans	[methyl-Co(III) methoxylated corrinoid protein OdmA] + ?	-	?
vanillate + [Co(I) methoxylated corrinoid protein OdmA]	-	Acetobacterium dehalogenans	[methyl-Co(III) methoxylated corrinoid protein OdmA] + 3,4-dihydroxybenzoate	-	?

Synonyms

Synonyms	Comment	Organism
OdmB	-	Acetobacterium dehalogenans
vanillate:corrinoid protein methyltransferase	-	Acetobacterium dehalogenans

General Information

General Information	Comment	Organism
physiological function	an ether-cleaving O-demethylase isolated from syringate-grown cells consists of four proteins, components A, B, C and D. The enzyme system converts only phenyl methyl ethers with a hydroxyl group in the ortho position to the methoxyl moiety. The presence of a carboxyl group in the aromatic compound is not required. Component B serves as vanillate:corrinoid protein methyltransferase (methyltransferase I) mediating the methyl transfer from vanillate to the reduced corrinoid protein component A	Acetobacterium dehalogenans

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Release 2023.1 (January 2023)