Literature summary for 2.1.1.359 extracted from

Kim, D.W.; Kim, K.B.; Kim, J.Y.; Seo, S.B.
Characterization of a novel histone H3K36 methyltransferase setd3 in zebrafish (2011), Biosci. Biotechnol. Biochem., 75, 289-294.

Search for more literature for 2.1.1.359

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Danio rerio

Organism

Organism	UniProt	Comment	Textmining
Danio rerio	Q7SXS7	-	-

Purification (Commentary)

Purification (Comment)	Organism
glutathione-Sepharose column chromatography	Danio rerio

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + histone H3(K36)	the enzyme has histone methyltransferase activity specifically towards mono-, di- and trimethylation of histone H3(K36) residues both in vitro and in vivo	Danio rerio	?	-	?

Synonyms

Synonyms	Comment	Organism
histone H3K36 methyltransferase	-	Danio rerio
HMTase	-	Danio rerio
setd3	-	Danio rerio

General Information

General Information	Comment	Organism
physiological function	the enzyme plays roles as an activator of general transcription and inhibits cell viability by inducing caspase-3 activation overexpression	Danio rerio

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Release 2023.1 (January 2023)