Literature summary for 2.1.1.182 extracted from

Kyuma, T.; Kizaki, H.; Ryuno, H.; Sekimizu, K.; Kaito, C.
16S rRNA methyltransferase KsgA contributes to oxidative stress resistance and virulence in Staphylococcus aureus (2015), Biochimie, 119, 166-174 .

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Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	-	-	-
Staphylococcus aureus RN4220	-	-	-

General Information

General Information	Comment	Organism
physiological function	knockout of KsgA attenuates the killing ability against silkworms. The KsgA knockout strain is sensitive to oxidative stress and has a lower survival rate in murine macrophages than the parent strain. The KsgA knockout strain exhibits decreased translational fidelity in oxidative stress conditions. Administration of N-acetyl-L-cysteine restores the killing ability of the knockout strain against silkworms	Staphylococcus aureus

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Release 2023.1 (January 2023)