KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.014 | - |
7,8-dihydrofolate | pH 6.8, 23°C | Methylorubrum extorquens | |
0.018 | - |
7,8-dihydrofolate | pH 6.8, 23°C | Methylorubrum extorquens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methylorubrum extorquens | Q8KQF2 | isoform DfrB | - |
Methylorubrum extorquens | Q8KQF3 | isoform DFRa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.011 | - |
substrate dihydrosarcinapterin, pH 6.8, 23°C | Methylorubrum extorquens |
0.041 | - |
substrate dihydrosarcinapterin, pH 6.8, 23°C | Methylorubrum extorquens |
3.13 | - |
substrate 7,8-dihydrofolate, pH 6.8, 23°C | Methylorubrum extorquens |
18.5 | - |
substrate 7,8-dihydrofolate, pH 6.8, 23°C | Methylorubrum extorquens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
7,8-dihydrofolate + NADPH + H+ | - |
Methylorubrum extorquens | 5,6,7,8-tetrahydrofolate + NADP+ | - |
? | |
dihydrosarcinapterin + NADPH + H+ | - |
Methylorubrum extorquens | tetrahydrosarcinapterin + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DfrA | - |
Methylorubrum extorquens |
DfrB | - |
Methylorubrum extorquens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
15 | 37 | broad | Methylorubrum extorquens |
23 | 40 | broad | Methylorubrum extorquens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.2 | - |
7,8-dihydrofolate | pH 6.8, 23°C | Methylorubrum extorquens | |
17 | - |
7,8-dihydrofolate | pH 6.8, 23°C | Methylorubrum extorquens |