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Literature summary for 1.4.3.4 extracted from

  • Yang, D.; Wang, R.; Zhu, J.; Cao, Q.; Qin, J.; Zhu, H.; Qian, S.
    Synthesis, crystal structures, molecular docking, vitro monoamine oxidase-B inhibitory activity of transition metal complexes with 2-{4-[bis (4-fluorophenyl)methyl]piperazin-1-yl} acetic acid (2017), J. Mol. Struct., 1128, 493-498 .
No PubMed abstract available
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
iproniazid phosphate
-
 Homo sapiens
iproniazid phosphate
-
 Rattus norvegicus
[Cu(2-[4-[bis(4-fluorophenyl)methyl]pipera-zin-1-yl]acetic acid)2(H2O)] the complex 1 is a potent MAO-B inhibitor Homo sapiens
[Cu(2-[4-[bis(4-fluorophenyl)methyl]pipera-zin-1-yl]acetic acid)2(H2O)] the complex 1 is a potent MAO-B inhibitor Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
outer mitochondrial membrane
-
 Homo sapiens
-
-
outer mitochondrial membrane
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P27338
-
-
Rattus norvegicus P19643
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
MAO-B
-
 Homo sapiens
MAO-B
-
 Rattus norvegicus
monoamine oxidase-B
-
 Homo sapiens
monoamine oxidase-B
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Homo sapiens
FAD
-
 Rattus norvegicus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00185
-
 pH and temperature not specified in the publication Rattus norvegicus [Cu(2-[4-[bis(4-fluorophenyl)methyl]pipera-zin-1-yl]acetic acid)2(H2O)]
0.00759
-
 pH and temperature not specified in the publication Rattus norvegicus iproniazid phosphate