Activating Compound | Comment | Organism | Structure |
---|---|---|---|
CoA | free CoA is a strong activator of the reductase reaction | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-methylcrotonyl-CoA | CoA-activated enzyme shows competitive inhibition with the substrate analog 2-methylcrotonyl-CoA | Bos taurus | |
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole | extremely potent inhibitor | Bos taurus | |
5,5'-dithiobis(2-nitrobenzoic acid) | extremely potent inhibitor | Bos taurus | |
acetyl-CoA | competitive inhibitor | Bos taurus | |
butyryl-CoA | competitive inhibitor | Bos taurus | |
iodoacetamide | - |
Bos taurus | |
iodoacetate | - |
Bos taurus | |
malonyl-CoA | noncompetitive inhibitor | Bos taurus | |
N-ethylmaleimide | extremely potent inhibitor | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mammary gland | - |
Bos taurus | - |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0029 | - |
2-methylcrotonyl-CoA | pH and temperature not specified in the publication | Bos taurus | |
0.005 | - |
butyryl-CoA | pH and temperature not specified in the publication | Bos taurus | |
0.006 | - |
acetyl-CoA | pH and temperature not specified in the publication | Bos taurus | |
0.021 | - |
malonyl-CoA | pH and temperature not specified in the publication | Bos taurus |