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Literature summary for 1.3.1.85 extracted from

  • Ray, L.; Valentic, T.R.; Miyazawa, T.; Withall, D.M.; Song, L.; Milligan, J.C.; Osada, H.; Takahashi, S.; Tsai, S.C.; Challis, G.L.
    A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units (2016), Nat. Commun., 7, 13609.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
crotonyl-CoA + CO2 + NADPH + H+ Streptomyces ambofaciens
-
?
-
?
crotonyl-CoA + CO2 + NADPH + H+ Streptomyces ambofaciens ATCC23877
-
?
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces ambofaciens
-
-
-
Streptomyces ambofaciens ATCC23877
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E)-oct-2-enoyl-CoA + NADPH + CO2 + H+
-
Streptomyces ambofaciens (2S)-2-carboxyoctanoyl-CoA + NADP+
-
?
(2E)-oct-2-enoyl-CoA + NADPH + CO2 + H+
-
Streptomyces ambofaciens ATCC23877 (2S)-2-carboxyoctanoyl-CoA + NADP+
-
?
crotonyl-CoA + CO2 + NADPH + H+
-
Streptomyces ambofaciens ?
-
?
crotonyl-CoA + CO2 + NADPH + H+
-
Streptomyces ambofaciens ATCC23877 ?
-
?

Synonyms

Synonyms Comment Organism
CCRC
-
Streptomyces ambofaciens
crotonyl-CoA reductase-carboxylase
-
Streptomyces ambofaciens

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Streptomyces ambofaciens