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Literature summary for 1.3.1.78 extracted from
- Molecular and biochemical characterization of an Arabidopsis thaliana arogenate dehydrogenase with two highly similar and active protein domains (2002), Plant Mol. Biol., 48, 361-368.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| tyrA gene, overexpression in Escherichia coli, 3 different plasmids TyrA-ATcM36, TyrA-ATlM36, TyrA-AT2 | Arabidopsis thaliana |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-tyrosine | - |
Arabidopsis thaliana |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.02 | - |
NADP+ | recombinant from plasmid TyrA-AT2 | Arabidopsis thaliana | |
| 0.04 | - |
NADP+ | recombinant from plasmid TyrA-ATcM36 | Arabidopsis thaliana | |
| 0.045 | - |
L-arogenate | recombinant from plasmids TyrA-AT2 and TyrA-ATlM36 | Arabidopsis thaliana | |
| 0.07 | - |
L-arogenate | recombinant from plasmid TyrA-ATcM36 | Arabidopsis thaliana | |
| 0.075 | - |
NADP+ | recombinant from plasmid TyrA-ATlM36 | Arabidopsis thaliana | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-arogenate + NAD+ | Arabidopsis thaliana | - |
L-tyrosine + NADH + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-arogenate + NAD(P)+ | - |
Arabidopsis thaliana | L-tyrosine + NAD(P)H + CO2 | - |
? | |
| L-arogenate + NAD+ | - |
Arabidopsis thaliana | L-tyrosine + NADH + CO2 | - |
? | |
| prephenate + NAD(P)+ | not prephenate | Arabidopsis thaliana | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cyclohexadienyl dehydrogenase | - |
Arabidopsis thaliana |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Arabidopsis thaliana |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Arabidopsis thaliana | |
| NADP+ | - |
Arabidopsis thaliana | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
L-tyrosine | recombinant from plasmid TyrA-ATlM36 | Arabidopsis thaliana | |
| 0.012 | - |
L-tyrosine | recombinant from plasmid TyrA-AT2 | Arabidopsis thaliana | |
| 0.014 | - |
L-tyrosine | recombinant from plasmid TyrA-ATcM36 | Arabidopsis thaliana | |
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