Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | moderate | Homo sapiens | |
ADP | moderate | Rattus norvegicus | |
ATP | moderate | Homo sapiens | |
ATP | moderate | Rattus norvegicus | |
Koningic acid | inhibition of both classical enzymic and arsentate reductase activities of glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens | |
Koningic acid | inhibition of both classical enzymic and arsentate reductase activities of glyceraldehyde-3-phosphate dehydrogenase | Rattus norvegicus | |
NADH | strong | Homo sapiens | |
NADH | strong | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | besides glyceraldehyde-3-phosphate dehydrogenase, presence of other enzymes contributing to arsenate reduction | Rattus norvegicus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
glyceraldehyde-3-phosphate dehydrogenase working as arsenate reductase | - |
Rattus norvegicus | - |
glyceraldehyde-3-phosphate dehydrogenase working as arsenate reductase | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
arsenate + glutathione + glutaredoxin = arsenite + a glutaredoxin-glutathione disulfide + H2O | arsenate reduction by glyceraldehyde-3-phosphate dehydrogenase may take place during or as a consequence of, the arsenolytic cleavage of the thioester bond formed between the enzymes C149 and the 3-phosphoglycerol moiety of the substrate | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arsenate + reduced glutathione + NAD+ + glyceraldehyde-3-phosphate | - |
Homo sapiens | arsenite + glutathione + ? | - |
? | |
arsenate + reduced glutathione + NAD+ + glyceraldehyde-3-phosphate | - |
Rattus norvegicus | arsenite + glutathione + ? | - |
? |