Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.3.3 extracted from

  • Spellerberg, B.; Cundell, D.R.; Sandros, J.; Pearce, B.J.; Idänpään-Heikkilä, I.; Rosenow, C.; Masure, H.R.
    Pyruvate oxidase, as a determinant of virulence in Streptococcus pneumoniae (1996), Mol. Microbiol., 19, 803-813.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + phosphate + O2 + H2O Streptococcus pneumoniae contribution to attachment to glycoconjugates of nasopharyngeal cell receptor, type II lung cells and human endothelial cells acetyl phosphate + CO2 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Streptococcus pneumoniae
-
analysis of a pyruvate oxidase deficient mutant, that fails to attach to human endothelial and type II lung cells and to nasopharyngeal cell receptor
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + phosphate + O2 + H2O contribution to attachment to glycoconjugates of nasopharyngeal cell receptor, type II lung cells and human endothelial cells Streptococcus pneumoniae acetyl phosphate + CO2 + H2O2
-
?

Cofactor

Cofactor Comment Organism Structure
FAD
-
Streptococcus pneumoniae
thiamine diphosphate
-
Streptococcus pneumoniae