Literature summary for 1.14.14.86 extracted from

Todoroki, Y.; Naiki, K.; Muramatsu, T.; Ohnishi, T.; Ueno, K.; Mizutani, M.; Hirai, N.
A conformationally restricted uniconazole analogue as a specific inhibitor of rice ent-kaurene oxidase, CYP701A6 (2012), Bioorg. Med. Chem. Lett., 22, 3240-3243 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
(5E)-6-tert-butyl-5-[(4-chlorophenyl)methylidene]-5,6-dihydro-8H-[1,2,4]triazolo[5,1-c][1,4]oxazine	-	Oryza sativa Japonica Group
(5E)-6-tert-butyl-5-[(4-nitrophenyl)methylidene]-5,6-dihydro-8H-[1,2,4]triazolo[5,1-c][1,4]oxazine	-	Oryza sativa Japonica Group

Organism

Organism	UniProt	Comment	Textmining
Oryza sativa Japonica Group	Q5Z5R4	-	-

Subunits

Subunits	Comment	Organism
?	x * 50000, SDS-PAGE, x * 56000, calculated	Oryza sativa Japonica Group

Synonyms

Synonyms	Comment	Organism
CYP701A6	-	Oryza sativa Japonica Group
ent-kaurene oxidase 2	-	Oryza sativa Japonica Group

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.000153	-	pH not specified in the publication, temperature not specified in the publication	Oryza sativa Japonica Group	(5E)-6-tert-butyl-5-[(4-nitrophenyl)methylidene]-5,6-dihydro-8H-[1,2,4]triazolo[5,1-c][1,4]oxazine
0.000231	-	pH not specified in the publication, temperature not specified in the publication	Oryza sativa Japonica Group	(5E)-6-tert-butyl-5-[(4-chlorophenyl)methylidene]-5,6-dihydro-8H-[1,2,4]triazolo[5,1-c][1,4]oxazine

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Release 2023.1 (January 2023)