Application | Comment | Organism |
---|---|---|
medicine | CYP46A1 affects the pathophysiology of AD and provides insight into how polymorphisms in the CYP46A1 gene might influence the pathophysiology of this prevalent disease | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | CYP46A1 affects the pathophysiology of Alzheimers' disease and provides insight into how polymorphisms in the CYP46A1 gene might influence the pathophysiology of this prevalent disease | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | in normal brain | Homo sapiens | - |
brain | in neurons and some astrocytes in the normal brain, in Alzheimer's disease the enzyme shows prominent expression in astrocytes and around amyloid plaques | Homo sapiens | - |
neuron | in normal brain | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CYP46A1 affects the pathophysiology of Alzheimers' disease and provides insight into how polymorphisms in the CYP46A1 gene might influence the pathophysiology of this prevalent disease | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP46A1 | - |
Homo sapiens |