Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17beta-(1-p-chlorophenyl-3-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-chlorophenyl-3-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-chlorophenyl-5-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-chlorophenyl-5-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-cyanophenyl-3-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-cyanophenyl-3-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-cyanophenyl-5-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-cyanophenyl-5-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-methoxyphenyl-3-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-methoxyphenyl-3-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-methoxyphenyl-5-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-methoxyphenyl-5-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-tolyl-3-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-tolyl-5-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-p-tolylphenyl-3-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-p-tolylphenyl-5-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-phenyl-3-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-phenyl-3-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
17beta-(1-phenyl-5-pyrazolyl)androst-4-en-3-one | - |
Rattus norvegicus | |
17beta-(1-phenyl-5-pyrazolyl)androst-5-en-3beta-ol | - |
Rattus norvegicus | |
additional information | inhibitory effects of synthesized 3beta-hydroxy-17beta-exo-heterocyclic steroids and the corresponding DELTA4-3-ketosteroids on the testicular C17,20-lyase activity are analyzed by an in vitro radioligand incubation technique, overview | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
17alpha-hydroxylase/C(17,20)-lyase | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.022 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 17beta-(1-p-cyanophenyl-3-pyrazolyl)androst-4-en-3-one | |
0.059 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 17beta-(1-phenyl-5-pyrazolyl)androst-4-en-3-one |