Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2alpha-hydroxytaxusin + [reduced NADPH-hemoprotein reductase] + O2 | Taxus cuspidata | - |
2alpha,7beta-dihydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
taxusin + [reduced NADPH-hemoprotein reductase] + O2 | Taxus cuspidata | - |
7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Taxus cuspidata | Q6JTJ0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2alpha-hydroxytaxusin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Taxus cuspidata | 2alpha,7beta-dihydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
taxusin + [reduced NADPH-hemoprotein reductase] + O2 | - |
Taxus cuspidata | 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Taxus cuspidata |
General Information | Comment | Organism |
---|---|---|
physiological function | taxusin is hydroxylated by both taxoid 7beta-hydroxylase and taxoid 2alpha-hydroxylase, and both enzymes are capable of the reciprocal conversion of their respective pentaol tetraacetate products to the hexaol tetraacetate | Taxus cuspidata |