Literature summary for 1.14.14.14 extracted from

Siddiqui, M.; Atia-tul-Waha, A.; Naveed Shaikh, N.; Baydoun, E.; Atta-ur-Rahma, A.; Choudhary, M.
Biocatalytic transformation of steroidal drugs oxandrolone and ganaxolone, and aromatase inhibitory activity of transformed products (2021), Phytochem. Lett., 44, 137-141 .

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
17beta,11alpha-dihydroxy-17alpha-methylandrosta-2-oxa-4-ene-3-one	-	Homo sapiens
ganaxolone	steroidal anti-epileptic drug	Homo sapiens
oxandrolone	steroidal anabolic drug	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P11511	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
CYP19A1	-	Homo sapiens

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0006	-	pH 7.4, 37°C	Homo sapiens	17beta,11alpha-dihydroxy-17alpha-methylandrosta-2-oxa-4-ene-3-one
0.00081	-	pH 7.4, 37°C	Homo sapiens	oxandrolone
0.00138	-	pH 7.4, 37°C	Homo sapiens	ganaxolone

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Release 2023.1 (January 2023)