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Literature summary for 1.14.14.14 extracted from
- Profile of CYP19A1 mRNA expression and aromatase activity during syncytialization of primary human villous trophoblast cells at term (2018), Biochimie, 148, 12-17 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P11511 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cytotrophoblast | villous cytotrophoblast cells | Homo sapiens | - |
| placenta | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CYP19A1 | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | dexamethasone (100 nM) and vascular endothelial growth factor (5 ng/ml) decrease CYP19A1 mRNA levels, while having no effect on aromatase activity | down |
| Homo sapiens | CYP19A1 mRNA levels and aromatase activity in villous cytotrophoblast cells reach a maximum after about 48 h of culture | additional information |
| Homo sapiens | forskolin (10 mM) and myristate acetate (1 mM) increases CYP19A1 mRNA levels by 1.8- and 1.6fold, respectively, as well as inducing aromatase catalytic activity | up |
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