Protein Variants | Comment | Organism |
---|---|---|
A435Y | the mutant is active only with bicyclo[3.2.0]hept-2-en-6-one | Thermobifida fusca |
A435Y | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
A442G | the mutant shows 75% of wild type activity | Thermobifida fusca |
C65V | the mutant shows 94% of wild type activity | Thermobifida fusca |
C65V/I67T | the mutant shows 47% of wild type activity | Thermobifida fusca |
C65V/I67T/Q152F/S441A/A442G | the mutant shows 31% of wild type activity | Thermobifida fusca |
C65V/I67T/Q93W | the mutant shows 54% of wild type activity | Thermobifida fusca |
I339S | the mutant shows 81% of wild type activity | Thermobifida fusca |
I67T | the mutant shows 16% of wild type activity | Thermobifida fusca |
I67T/L338P | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
I67T/L338P/A435Y/A442G | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
I67T/L338P/A435Y/A442G/L443F/S444C | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
L153G | inactive | Thermobifida fusca |
L153G | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
L338P | the mutant shows 59% of wild type activity | Thermobifida fusca |
L443F | the mutant shows 65% of wild type activity | Thermobifida fusca |
L447P | the mutant shows 85% of wild type activity | Thermobifida fusca |
M446G | the mutant shows 49% of wild type activity and is able to convert 1-indanone to 1-isochromanone | Thermobifida fusca |
Q152F | the mutant shows 35% of wild type activity | Thermobifida fusca |
Q152F/A442G | the mutant shows 37% of wild type activity | Thermobifida fusca |
Q152F/S441A/A442G | the mutant shows 33% of wild type activity | Thermobifida fusca |
Q93W | the mutant shows 65% of wild type activity | Thermobifida fusca |
Q93W/A442G/S444C/M446G/L447P | the mutant shows 38% of wild type activity | Thermobifida fusca |
Q93W/S441A/A442G/S444C/M446G/L447P | the mutant shows 40% of wild type activity | Thermobifida fusca |
S441A | the mutant shows 73% of wild type activity | Thermobifida fusca |
S441A/A442G | the mutant shows 56% of wild type activity | Thermobifida fusca |
S441A/A442G/S444C/M446G/L447P | the mutant shows 41% of wild type activity | Thermobifida fusca |
S444C | the mutant shows 66% of wild type activity | Thermobifida fusca |
V54I | the mutant shows 65% of wild type activity | Thermobifida fusca |
V54I/C65V/I67T/Q93W/I339S/S441A/A442G/S444C/M446G/L447P | the mutant shows 5% of wild type activity | Thermobifida fusca |
V54I/C65V/I67T/Q93W/Q152F/I339S/S441A/A442G/S444C/M446G/L447P | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
V54I/C65V/I67T/Q93W/Q152F/L153G/I339S/S441A/A442G/S444C/M446G/L447P | the mutant shows less than 3% of wild type activity | Thermobifida fusca |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phenylacetone + NADPH + H+ + O2 | Thermobifida fusca | - |
benzyl acetate + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermobifida fusca | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
bicyclo[3.2.0]hept-2-en-6-one + NADPH + H+ + O2 | - |
Thermobifida fusca | ? | - |
? | |
phenylacetone + NADPH + H+ + O2 | - |
Thermobifida fusca | benzyl acetate + NADP+ + H2O | - |
? | |
thioanisole + NADPH + H+ + O2 | - |
Thermobifida fusca | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAMO | - |
Thermobifida fusca |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Thermobifida fusca | |
NADPH | - |
Thermobifida fusca |