Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + 3 NADPH + 3 H+ + 4 O2 | Rattus norvegicus | synthesis of the signaling molecule nitric oxide | 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P29476 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + 3 NADPH + 3 H+ + 4 O2 | - |
Rattus norvegicus | 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O | - |
? | |
L-arginine + 3 NADPH + 3 H+ + 4 O2 | synthesis of the signaling molecule nitric oxide | Rattus norvegicus | 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | during catalysis, NADPH-derived electrons are transfered into FAD and then distributed into the FMN domain for further transfer to internal or external heme groups. Conformational freedom of the FMN domain is essential for the electron transfer | Rattus norvegicus | |
FMN | during catalysis, NADPH-derived electrons are transfer into FAD and then distributed into the FMN domain for further transfer to internal or external heme groups. Conformational freedom of the FMN domain is essential for the electron transfer | Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
metabolism | synthesis of the signaling molecule nitric oxide | Rattus norvegicus |