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BRENDA support

Literature summary for 1.14.13.251 extracted from

  • Wargo, M.; Szwergold, B.; Hogan, D.
    Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism (2008), J. Bacteriol., 190, 2690-2699 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
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-
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Synonyms

Synonyms Comment Organism
GbcA
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Pseudomonas aeruginosa
GbcB
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Pseudomonas aeruginosa
PA5410
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Pseudomonas aeruginosa
PA5411
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Pseudomonas aeruginosa

Expression

Organism Comment Expression
Pseudomonas aeruginosa expression is induced by growth on glycine betaine or dimethylglycine as sole nitrogen sources up

General Information

General Information Comment Organism
physiological function PA5410 gene encodes a protein with homology to the large subunit of bacterial hydroxylating dioxygenases. The PA5411 gene encodes a probable flavin adenine dinucleotide-binding ferrodoxin reductase. A strain lacking the genes A5410/PA5411 is defective in growth on choline or glycine betaine but can grow on dimethylglycine. When grown in minimal medium with glucose or pyruvate as the sole carbon source, the growth rate of the mutant strain is indistinguishable from wild-type. The PA5410 and PA5411 genes are also necessary for the utilization of choline and glycine betaine as sole nitrogen sources but are not required for the utilization dimethylglycine, sarcosine, or lysine Pseudomonas aeruginosa