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Literature summary for 1.14.13.247 extracted from

  • Kumar, R.; Zhao, S.; Vetting, M.; Wood, B.; Sakai, A.; Cho, K.; Solbiati, J.; Almo, S.; Sweedler, J.; Jacobson, M.; Gerlt, J.; Cronan, J.
    Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine (2014), mBio, 5, e00933-13 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-proline betaine + NADH + H+ + O2 Paracoccus denitrificans L-proline betaine is also called N,N-dimethylproline or stachydrine N-methyl-L-proline + formaldehyde + NAD+ + H2O
-
?
L-proline betaine + NADH + H+ + O2 Cereibacter sphaeroides L-proline betaine is also called N,N-dimethylproline or stachydrine N-methyl-L-proline + formaldehyde + NAD+ + H2O
-
?
L-proline betaine + NADH + H+ + O2 Paracoccus denitrificans Pd1222 L-proline betaine is also called N,N-dimethylproline or stachydrine N-methyl-L-proline + formaldehyde + NAD+ + H2O
-
?
L-proline betaine + NADPH + H+ + O2 Paracoccus denitrificans L-proline betaine is also called N,N-dimethylproline or stachydrine N-methyl-L-proline + formaldehyde + NADP+ + H2O
-
?
L-proline betaine + NADPH + H+ + O2 Cereibacter sphaeroides L-proline betaine is also called N,N-dimethylproline or stachydrine N-methyl-L-proline + formaldehyde + NADP+ + H2O
-
?
L-proline betaine + NADPH + H+ + O2 Paracoccus denitrificans Pd1222 L-proline betaine is also called N,N-dimethylproline or stachydrine N-methyl-L-proline + formaldehyde + NADP+ + H2O
-
?

Organism

Organism UniProt Comment Textmining
Cereibacter sphaeroides
-
-
-
Paracoccus denitrificans
-
-
-
Paracoccus denitrificans Pd1222
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-proline betaine + NADH + H+ + O2 L-proline betaine is also called N,N-dimethylproline or stachydrine Paracoccus denitrificans N-methyl-L-proline + formaldehyde + NAD+ + H2O
-
?
L-proline betaine + NADH + H+ + O2 L-proline betaine is also called N,N-dimethylproline or stachydrine Cereibacter sphaeroides N-methyl-L-proline + formaldehyde + NAD+ + H2O
-
?
L-proline betaine + NADH + H+ + O2 L-proline betaine is also called N,N-dimethylproline or stachydrine Paracoccus denitrificans Pd1222 N-methyl-L-proline + formaldehyde + NAD+ + H2O
-
?
L-proline betaine + NADPH + H+ + O2 L-proline betaine is also called N,N-dimethylproline or stachydrine Paracoccus denitrificans N-methyl-L-proline + formaldehyde + NADP+ + H2O
-
?
L-proline betaine + NADPH + H+ + O2 L-proline betaine is also called N,N-dimethylproline or stachydrine Cereibacter sphaeroides N-methyl-L-proline + formaldehyde + NADP+ + H2O
-
?
L-proline betaine + NADPH + H+ + O2 L-proline betaine is also called N,N-dimethylproline or stachydrine Paracoccus denitrificans Pd1222 N-methyl-L-proline + formaldehyde + NADP+ + H2O
-
?

Synonyms

Synonyms Comment Organism
HpbB1-HpbC1
-
Paracoccus denitrificans
HpbB1-HpbC1
-
Cereibacter sphaeroides
HpbB2-HpbC2
-
Paracoccus denitrificans
HpbB2-HpbC2
-
Cereibacter sphaeroides

Cofactor

Cofactor Comment Organism Structure
NADH
-
Paracoccus denitrificans
NADH
-
Cereibacter sphaeroides
NADPH
-
Paracoccus denitrificans
NADPH
-
Cereibacter sphaeroides