Application | Comment | Organism |
---|---|---|
degradation | in soil conditions, Phomopsis liquidambari effectively decomposes 99% of the available 4-hydroxybenzoic acid within 48 h. 4-Hydroxybenzoic acid hydroxylase activity is present in a high level early at 20 h, followed by 3,4-dihydroxybenzoic acid decarboxylase which reaches its highest relative activity at 24 h, and finally catechol 1,2-dioxygenase exhibits peak activity at 32 h | Diaporthe liquidambaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxybenzoate + NADPH + H+ + O2 | Diaporthe liquidambaris | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | protocatechuate + NADP+ + H2O | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | ? | |
4-hydroxybenzoate + NADPH + H+ + O2 | Diaporthe liquidambaris B3 | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | protocatechuate + NADP+ + H2O | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | ? |
Organism | UniProt | Comment | Textmining |
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Diaporthe liquidambaris | - |
- |
- |
Diaporthe liquidambaris B3 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxybenzoate + NADPH + H+ + O2 | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | Diaporthe liquidambaris | protocatechuate + NADP+ + H2O | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | ? | |
4-hydroxybenzoate + NADPH + H+ + O2 | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | Diaporthe liquidambaris B3 | protocatechuate + NADP+ + H2O | 4-hydroxybenzoate degradation proceeds via hdroxylation to 3,4-dihydroxybenzoic acid and then conversion to catechol, which is cleaved to cis,cis-muconic acid through ortho-catechol cleavage | ? |