Crystallization (Comment) | Organism |
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crystal structure of the enzyme bound to NADP+ and L-ornithine (1.9 A resolution), crystal structure of the enzyme bound to NADP+ and L-lysine (2.28 A resolution), crystal structure of the enzyme (reduced state) bound to NADPH (2.32 A resolution), crystal structure of the enzyme (reduced state) bound to NADP+ and L-arginine (2.9 A resolution), crystal structure of the enzyme (re-oxidized state) bound to NADP+ and L-ornithine (2.75 A resolution), crystal structure of the enzyme (re-oxidized state) bound to NADP+ and L-arginine (2.29 A resolution), crystal structure of the enzyme bound to L-ornithine (2.3 A resolution) | Aspergillus fumigatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine + NADH + H+ + O2 | Aspergillus fumigatus | the enzyme catalyzes the generation of N5-hydroxyornithine in the biosynthesis of siderophores, a reaction essential for virulence | N5-hydroxy-L-ornithine + NAD+ + H2O | - |
? | |
L-ornithine + NADPH + H+ + O2 | Aspergillus fumigatus | the enzyme catalyzes the generation of N5-hydroxyornithine in the biosynthesis of siderophores, a reaction essential for virulence | N5-hydroxy-L-ornithine + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus fumigatus | Q5SE95 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine + NADH + H+ + O2 | the enzyme catalyzes the generation of N5-hydroxyornithine in the biosynthesis of siderophores, a reaction essential for virulence | Aspergillus fumigatus | N5-hydroxy-L-ornithine + NAD+ + H2O | - |
? | |
L-ornithine + NADPH + H+ + O2 | the enzyme catalyzes the generation of N5-hydroxyornithine in the biosynthesis of siderophores, a reaction essential for virulence | Aspergillus fumigatus | N5-hydroxy-L-ornithine + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SidA | - |
Aspergillus fumigatus |