Literature summary for 1.14.11.68 extracted from

Gao, J.; Gu, J.; Pan, X.; Gan, X.; Ju, Z.; Zhang, S.; Xia, Y.; Lu, L.; Wang, X.
Blockade of miR-142-3p promotes anti-apoptotic and suppressive function by inducing KDM6A-mediated H3K27me3 demethylation in induced regulatory T cells (2019), Cell Death Dis., 10, 332 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15550	-	-

General Information

General Information	Comment	Organism
physiological function	microRNA miR-142-3p binds directly to lysine demethylase 6A (KDM6A), which results in demethylation of H3K27me3 and in turn upregulated expression of the anti-apoptotic protein Bcl-2. miR-142-3p knockdown increases autophagy-related protein 16-1-mediated autophagy in in vitro induced human regulatory T cells	Homo sapiens

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Release 2023.1 (January 2023)