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Literature summary for 1.14.11.67 extracted from
- Targeting of histone demethylases KDM5A and KDM6B inhibits the proliferation of temozolomide-resistant glioblastoma cells (2019), Cancers (Basel), 11, 878 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| JIB 04 | inhibitor is active against native and temozolomide-resistant glioblastoma cells. GSK J4, inhibitor of lysine demethylase KDM6B, EC 1.14.11.68, and JIB 04 strongly synergize and are a potent combination against temozolomide-resistant glioblastoma cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P29375 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KDM5A | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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