Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cysteine | 1 mM Fe2+ plus 2 mM cysteine required | Sus scrofa |
Cloned (Comment) | Organism |
---|---|
open reading frame of 849 base pairs | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5.9 | - |
myo-inositol | with Fe(2+) and L-cysteine as activators | Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | 1 mM Fe2+ plus 2mM cysteine required | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32663 | - |
electrospray MS determination, gel filtration, SDS-PAGE, sedimentation equilibirum, enzyme does not undergo oligomerization in the presence of myo-inositol | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
myo-inositol + O2 | Sus scrofa | major role in pathogenesis of diabetis | d-glucuronate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | Q8WN98 | SwissProt Accession Code:Q8WN98 | - |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-chiro-inositol + O2 | much less active with D-chiro-inositol than with myo-inositol | Sus scrofa | D-glucuronate | - |
? | |
myo-inositol + O2 | highly specific for myo-inositol | Sus scrofa | D-glucuronate + H2O | - |
? | |
myo-inositol + O2 | major role in pathogenesis of diabetis | Sus scrofa | d-glucuronate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 32663, electrospray MS determination, gel filtration, SDS-PAGE, sedimentation equilibirum, enzyme does not undergo oligomerization in the presence of myo-inositol | Sus scrofa |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.183 | - |
myo-inositol | with Fe(2+) and L-cysteine as activators | Sus scrofa |