Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.13.11.5 extracted from

  • Yang, W.; Ruan, L.; Tao, J.; Peng, D.; Zheng, J.; Sun, M.
    Single amino acid substitution in homogentisate dioxygenase affects melanin production in Bacillus thuringiensis (2018), Front. Microbiol., 9, 2242 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
D120A transformant shows a non-pigmented phenotype Bacillus thuringiensis
F136A transformant shows a pigmented phenotype Bacillus thuringiensis
G119A transformant shows a non-pigmented phenotype Bacillus thuringiensis
G128A transformant shows a pigmented phenotype Bacillus thuringiensis
G241A transformant shows a pigmented phenotype Bacillus thuringiensis
G272E mutation is responsible for pigment overproduction in Bacillus thuringiensis BMB181 Bacillus thuringiensis
G323A transformant shows a non-pigmented phenotype Bacillus thuringiensis
G89A transformant shows a non-pigmented phenotype Bacillus thuringiensis
H261A transformant shows a pigmented phenotype Bacillus thuringiensis
H334A transformant shows a pigmented phenotype Bacillus thuringiensis
K219A transformant shows a non-pigmented phenotype Bacillus thuringiensis
N116A transformant shows a non-pigmented phenotype Bacillus thuringiensis
N300A transformant shows a non-pigmented phenotype Bacillus thuringiensis
P245A transformant shows a non-pigmented phenotype Bacillus thuringiensis
P336A transformant shows a pigmented phenotype Bacillus thuringiensis

Organism

Organism UniProt Comment Textmining
Bacillus thuringiensis ADH05034.1
-
-
Bacillus thuringiensis BMB171 ADH05034.1
-
-

Synonyms

Synonyms Comment Organism
HmgA
-
Bacillus thuringiensis

General Information

General Information Comment Organism
malfunction disruption of the hmgA gene encoding homogentisate dioxygenase in BMB171 induces the accumulation of the homogentisic acid and provokes an increased pigment (pyomelanin) formation Bacillus thuringiensis