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Literature summary for 1.13.11.5 extracted from
- Molecular docking analysis of nitisinone with homogentisate 1,2 dioxygenase (2017), Bioinformation, 13, 136-139 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| nitisinone | competitive inhibitor | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q93099 | - |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | alkaptonuria is an inherited disease that is caused by homogenticate accumulation. Deficiency or mutation in homogentisate 1,2-dioxygenase gene (chromosome 3q21-q23) lead to production of incorrectly folded or truncated enzyme | Homo sapiens |
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Release 2023.1 (January 2023)
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