Organism | UniProt | Comment | Textmining |
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synthetic construct | - |
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General Information | Comment | Organism |
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metabolism | iron(II) complexes [Fe(L)(MeCN)3](SO3CF3)2 (L are two derivatives of tris(2-pyridyl)-based ligands) as models for cysteine dioxygenase. The molecular structure of one of the complexes exhibits octahedral coordination geometry, and the Fe-Npy bond lengths are similar to those in the Cys-bound FeII-CDO. The iron(II) centers of the complexes exhibit relatively high FeIII/II redox potentials E1/2 0.988-1.380 V vs. ferrocene/ferrocenium electrode. The reaction of in situ generated [Fe(L)(MeCN)(SPh)]+ with excess O2 in acetonitrile yields selectively the doubly oxygenated phenylsulfinic acid product. Both oxygen atoms of O2 are incorporated into the product. A FeIII peroxido intermediate with a rhombic S=1=2 FeIII center is involved in the reaction | synthetic construct |