Literature summary for 1.11.1.8 extracted from

Lou, Y.; Ji, G.; Liu, Q.; Wang, P.; Zhang, R.; Zhang, Y.; Liu, X.
Secretory expression and scale-up production of recombinant human thyroid peroxidase via baculovirus/insect cell system in a wave-type bioreactor (2018), Protein Expr. Purif., 149, 7-12 .

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Application

Application	Comment	Organism
synthesis	baculovirus-mediated expression of a truncated recombinant TPO proteine. The signal peptide from the peptidyl-glycine alpha-amidating monooxygenase significantly promotes the secretion in High Five cells when fused to TPO. An optimized scale-up production procedure for TPOt in a 5-L wave-type bioreactor and subsequent purification achieving a protein purity of >95% give a protein with high sensitivity and specificity in reactions with positive or negative human serum samples via the double-antigen sandwich method	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P07202	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)