Protein Variants | Comment | Organism |
---|---|---|
additional information | existence of a naturally occurring feedback inhibition-resistant mutant | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dihydroxyacetone phosphate | noncompetitive versus NADP+ | Escherichia coli | |
NADP+ | competitive versus NADPH | Escherichia coli | |
NADPH | competitive versus NADP+ | Escherichia coli | |
sn-glycerol-3-phosphate | product inhibition at an allosteric, regulatory site, competitive versus dihydroxyacetone phosphate, noncompetitive versus NADPH, the wild-type enzyme is feedback inhibited | Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics and bimolecular kinetic mechanism | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycerone phosphate + NAD(P)H + H+ | Escherichia coli | enzyme regulation, overview | sn-glycerol 3-phosphate + NAD(P)+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | bimolecular kinetic mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycerone phosphate + NAD(P)H + H+ | i.e. dihydroxyacetone phosphate | Escherichia coli | sn-glycerol 3-phosphate + NAD(P)+ | - |
r | |
glycerone phosphate + NAD(P)H + H+ | enzyme regulation, overview | Escherichia coli | sn-glycerol 3-phosphate + NAD(P)+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
sn-glycerol-3-phosphate dehydrogenase | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
23 | - |
assay at | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Escherichia coli | |
NADH | - |
Escherichia coli | |
NADP+ | - |
Escherichia coli | |
NADPH | - |
Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics | Escherichia coli | |
0.0044 | - |
sn-glycerol-3-phosphate | pH 7.4, 23°C, wild-type enzyme | Escherichia coli | |
0.043 | - |
sn-glycerol-3-phosphate | pH 7.4, 23°C, resistant mutant enzyme | Escherichia coli |