Cloned (Comment) | Organism |
---|---|
genes CrGPDH1, CrGPDH2, and CrGPDH3, DNA and amino acid sequence determination and analysis, phylogenetic analysis | Chlamydomonas reinhardtii |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Chlamydomonas reinhardtii | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sn-glycerol 3-phosphate + NAD+ | Chlamydomonas reinhardtii | - |
glycerone phosphate + NADH + H+ | - |
r | |
sn-glycerol 3-phosphate + NAD+ | Chlamydomonas reinhardtii CC-125 | - |
glycerone phosphate + NADH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chlamydomonas reinhardtii | - |
three GPDH genes, CrGPDH1, CrGPDH2, and CrGPDH3 | - |
Chlamydomonas reinhardtii CC-125 | - |
three GPDH genes, CrGPDH1, CrGPDH2, and CrGPDH3 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sn-glycerol 3-phosphate + NAD+ | - |
Chlamydomonas reinhardtii | glycerone phosphate + NADH + H+ | - |
r | |
sn-glycerol 3-phosphate + NAD+ | - |
Chlamydomonas reinhardtii CC-125 | glycerone phosphate + NADH + H+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
More | each one of the three CrGPDHs has a bi-domain protein structure: a GPDH domain of about 350 amino acids located at the C terminus, and a phosphoserine phosphatase (SerB) domain of about 200 amino acids at the N terminus. The GPDH domain of all three CrGPDHs contains the conserved GSGAWA motif at residues 261-266 (CrGPDH1), 316-321 (CrGPDH2), and 267-272 (CrGPDH3), three-dimensional structures by homology modeling, based on the Homo sapiens GPD1 crystal structure, overview | Chlamydomonas reinhardtii |
Synonyms | Comment | Organism |
---|---|---|
glycerol-3-phosphate dehydrogenase | - |
Chlamydomonas reinhardtii |
GPDH | - |
Chlamydomonas reinhardtii |
NAD+-GPDH | - |
Chlamydomonas reinhardtii |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Chlamydomonas reinhardtii | |
NADH | - |
Chlamydomonas reinhardtii |