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Literature summary for 1.1.1.8 extracted from

  • Kao, C.C.; Wu, B.T.; Tsuei, Y.W.; Shih, L.J.; Kuo, Y.L.; Kao, Y.H.
    Green tea catechins: inhibitors of glycerol-3-phosphate dehydrogenase (2010), Planta Med., 76, 694-696.
    View publication on PubMed

Application

Application Comment Organism
nutrition green tea catechin (-)-epigallocatechin-3-gallate is a noncompetitive inhibitor of glycerol-3-phosphate dehydrogenase Oryctolagus cuniculus

Inhibitors

Inhibitors Comment Organism Structure
(-)-epigallocatechin-3-gallate noncompetitive Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Oryctolagus cuniculus
-
muscle
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroxyacetone phosphate + NADH + H+
-
Oryctolagus cuniculus sn-glycerol 3-phosphate + NAD+
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.02
-
(-)-epigallocatechin-3-gallate substrate dihydroxyacetone phosphate, pH 7.4, 25┬░C Oryctolagus cuniculus
0.02
-
(-)-epigallocatechin-3-gallate substrate NADH, pH 7.4, 25┬░C Oryctolagus cuniculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.02
-
pH 7.4, 25┬░C Oryctolagus cuniculus (-)-epigallocatechin-3-gallate