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Literature summary for extracted from

  • Ou, X.; Ji, C.; Han, X.; Zhao, X.; Li, X.; Mao, Y.; Wong, L.L.; Bartlam, M.; Rao, Z.
    Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1) (2006), J. Mol. Biol., 357, 858-869.
    View publication on PubMed


Cloned (Comment) Organism
expression in Escherichia coli BL-21 DE3 as a fusion protein with glutathione S-transferase Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapor-diffusion method enzyme/NAD+ complex, enzyme/dihydroxyacetonephosphate complex, enzyme/NAD+/dihydroxyacetonephosphate complex Homo sapiens


Organism UniProt Comment Textmining
Homo sapiens P21695

Purification (Commentary)

Purification (Comment) Organism
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroxyacetone phosphate + NADH an electrophilic catalytic mechanism by the epsilon-NH3+ group of Lys204 is proposed on the basis of the structural analysis Homo sapiens sn-glycerol 3-phosphate + NAD+


Synonyms Comment Organism
glycerol 3-phosphate dehydrogenase 1
Homo sapiens
Homo sapiens


Cofactor Comment Organism Structure
Homo sapiens