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Literature summary for 1.1.1.8 extracted from

  • Cai, J.; Pietzsch, M.; Theobald, U.; Rizzi, M.
    Fast purification and kinetic studies of the glycerol-3-phosphate dehydrogenase from the yeast Saccharomyces cerevisiae (1996), Biotechnology, 49, 19-27.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
NAD+ competitive inhibitor to NADH at physiological concentration Saccharomyces cerevisiae
phosphate competitive inhibitor against dihydroxyacetone phosphate, non-competitive inhibitor against NADH Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycerol 3-phosphate + NAD+ Saccharomyces cerevisiae
-
dihydroxyacetone phosphate + NADH + H+
-
?
sn-glycerol 3-phosphate + NAD+ Saccharomyces cerevisiae YSH 11-6B
-
dihydroxyacetone phosphate + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae YSH 11-6B
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharomyces cerevisiae

Reaction

Reaction Comment Organism Reaction ID
sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+ equilibrium random-bi-bi reaction mechanism Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [┬Ámol/min/mg] Specific Activity Maximum [┬Ámol/min/mg] Comment Organism
50.1
-
-
Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sn-glycerol 3-phosphate + NAD+
-
Saccharomyces cerevisiae dihydroxyacetone phosphate + NADH + H+
-
?
sn-glycerol 3-phosphate + NAD+
-
Saccharomyces cerevisiae YSH 11-6B dihydroxyacetone phosphate + NADH + H+
-
?

Subunits

Subunits Comment Organism
? x * 43000-47000, SDS-PAGE Saccharomyces cerevisiae

Temperature Optimum [┬░C]

Temperature Optimum [┬░C] Temperature Optimum Maximum [┬░C] Comment Organism
51
-
-
Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
most active Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Saccharomyces cerevisiae
NADH
-
Saccharomyces cerevisiae