Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
A203V | inactive enzyme | Homo sapiens |
M235V | inactive enzyme | Homo sapiens |
R80Q | - |
Homo sapiens |
S232L | inactive enzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-estradiol + NADP+ | Homo sapiens | - |
estrone + NADPH | - |
r | |
testosterone + NADP+ | Homo sapiens | 17beta-hydroxysterod dehydrogenase 3, reduction of androst-4-ene-3,17-dione is preferred | androst-4-ene-3,17-dione + NADPH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-estradiol + NADP+ | - |
Homo sapiens | estrone + NADPH | - |
r | |
testosterone + NADP+ | 17beta-hydroxysteroid dehydrogenase 3, reduction of androst-4-ene-3,17-dione is preferred | Homo sapiens | androst-4-ene-3,17-dione + NADPH + H+ | - |
r | |
testosterone + NADP+ | 17beta-hydroxysterod dehydrogenase 3, reduction of androst-4-ene-3,17-dione is preferred | Homo sapiens | androst-4-ene-3,17-dione + NADPH + H+ | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Homo sapiens |