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Literature summary for 1.1.1.40 extracted from

  • Munoz-Vargas, M.A.; Gonzalez-Gordo, S.; Palma, J.M.; Corpas, F.J.
    Inhibition of NADP-malic enzyme activity by H2S and NO in sweet pepper (Capsicum annuum L.) fruits (2020), Physiol. Plant., 168, 278-288 .
    View publication on PubMed
Search for more literature for 1.1.1.40

Inhibitors

Inhibitors Comment Organism Structure
Diethylamine NONOate 35% inhibition at 5 mM Capsicum annuum
additional information peroxynitrite does not affect the enzyme even at a high concentration of 5 mM 3-morpholinosydnonimine Capsicum annuum
Na2S the enzyme activity is inhibited by up to 29-32% using 2 and 5 mM Na2S as H2S donor Capsicum annuum
S-nitrosocysteine 35% inhibition at 5 mM Capsicum annuum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NADP+ Capsicum annuum
-
 pyruvate + CO2 + NADPH + H+
-
 r
pyruvate + CO2 + NADPH + H+ Capsicum annuum
-
 (S)-malate + NADP+
-
 r

Organism

Organism UniProt Comment Textmining
Capsicum annuum
-
 cultivar Melchor
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit
-
 Capsicum annuum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NADP+
-
 Capsicum annuum pyruvate + CO2 + NADPH + H+
-
 r
pyruvate + CO2 + NADPH + H+
-
 Capsicum annuum (S)-malate + NADP+
-
 r

Synonyms

Synonyms Comment Organism
NADP-malic enzyme
-
 Capsicum annuum
NADP-ME
-
 Capsicum annuum

Expression

Organism Comment Expression
Capsicum annuum enzyme activity increases 1.5fold during fruit ripening up

General Information

General Information Comment Organism
physiological function the enzyme plays an important role in maintaining the supply of NADPH during pepper fruit ripening Capsicum annuum