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Literature summary for 1.1.1.353 extracted from

  • Yabe, K.; Chihaya, N.; Hamamatsu, S.; Sakuno, E.; Hamasaki, T.; Nakajima, H.; Bennett, J.W.
    Enzymatic conversion of averufin to hydroxyversicolorone and elucidation of a novel metabolic grid involved in aflatoxin biosynthesis (2003), Appl. Environ. Microbiol., 69, 66-73.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
versiconal + NADPH + H+ Aspergillus parasiticus
-
versiconol + NADP+
-
r
versiconal + NADPH + H+ Aspergillus parasiticus NIAH-26
-
versiconol + NADP+
-
r
versiconal hemiacetal acetate + NADPH + H+ Aspergillus parasiticus
-
versiconol acetate + NADP+
-
r
versiconal hemiacetal acetate + NADPH + H+ Aspergillus parasiticus NIAH-26
-
versiconol acetate + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Aspergillus parasiticus
-
-
-
Aspergillus parasiticus NIAH-26
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1'-hydroxyversicolorone + NADPH + H+
-
Aspergillus parasiticus versicolorone + NADP+
-
r
1'-hydroxyversicolorone + NADPH + H+
-
Aspergillus parasiticus NIAH-26 versicolorone + NADP+
-
r
versiconal + NADPH + H+
-
Aspergillus parasiticus versiconol + NADP+
-
r
versiconal + NADPH + H+
-
Aspergillus parasiticus NIAH-26 versiconol + NADP+
-
r
versiconal hemiacetal acetate + NADPH + H+
-
Aspergillus parasiticus versiconol acetate + NADP+
-
r
versiconal hemiacetal acetate + NADPH + H+
-
Aspergillus parasiticus NIAH-26 versiconol acetate + NADP+
-
r

Synonyms

Synonyms Comment Organism
VHA reductase II
-
Aspergillus parasiticus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Aspergillus parasiticus

General Information

General Information Comment Organism
metabolism the enzyme is specifically involved in aflatoxin biosynthesis Aspergillus parasiticus